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KMID : 0361020170600020049
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Korean Journal of Otolaryngology - Head and Neck Surgery
2017 Volume.60 No. 2 p.49 ~ p.54
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Oral Microbiome and Its Association with Oral Diseases
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Kwon Min-Su
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Abstract
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Microbiome means a holistic genomic information of microorganism which usually having symbiotic relationships confer benefits to human body. Breaches in the homeostasis between host and microorganism or alterations of the microbiome are well-known risk factors promoting human diseases. Oral cavity has hundreds of microbes and demonstrates chronic inflammatory conditions by interrelations among microorganisms, foreign bodies, alcohol, and smoking. Oral microbiome also demonstrates a growing evidence of its implication in the etiology of oral diseases including cancer and other systemic diseases. In this review paper, I would introduce to the associated human diseases with oral microbiome and the mechanism how changes in the oral microbiome with its microenvironment leads to the host diseases. And I would also suggest a new research field in otorhinolaryngology connected to oral microbiome.
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KEYWORD
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Cancer, Head and neck, Microbiome, Oral cavity, Oral mucositis
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